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Superior temporal lobe dysfunction and frontotemporal dysconnectivity in subjects at risk of psychosis and in first-episode psychosis. 2009;30(12):4129-4137Pub Med Google Scholar Crossref Fusar-Poli P, Howes OD, Allen P, Broome M, Valli I, Asselin MC, Grasby PM, Mc Guire PK.Abnormal frontostriatal interactions in people with prodromal signs of psychosis: a multimodal imaging study. 2010;67(7):683-691Pub Med Google Scholar Crossref Fusar-Poli P, Stone JM, Broome MR, Valli I, Mechelli A, Mc Lean MA, Lythgoe DJ, O'Gorman RL, Barker GJ, Mc Guire PK.Circle size reflects the weight a study obtained in the meta-regression.

The proportion of HR subjects who developed a frank psychotic episode is depicted on the Figure 4.

Meta-regression on the effects of age of subjects at clinical high risk (HR) and publication year on transition risks to psychosis.

Prediction of psychosis in adolescents and young adults at high risk: results from the prospective European Prediction of Psychosis Study. 2010;67(3):241-251Pub Med Google Scholar Crossref Perälä J, Suvisaari J, Saarni SI, Kuoppasalmi K, Isometsä E, Pirkola S, Partonen T, Tuulio-Henriksson A, Hintikka J, Kieseppä T, Härkänen T, Koskinen S, Lönnqvist J.

Lifetime prevalence of psychotic and bipolar I disorders in a general population. 2007;64(1):19-28Pub Med Google Scholar Crossref Yung AR, Phillips LJ, Mc Gorry PD, Mc Farlane CA, Francey S, Harrigan S, Patton GC, Jackson HJ.

Prodromal assessment with the Structured Interview for Prodromal Syndromes and the Scale of Prodromal Symptoms: predictive validity, interrater reliability, and training to reliability. 2003;29(4):703-715Pub Med Google Scholar Crossref Yung AR, Yuen HP, Mc Gorry PD, Phillips LJ, Kelly D, Dell’Olio M, Francey SM, Cosgrave EM, Killackey E, Stanford C, Godfrey K, Buckby J.

Mapping the onset of psychosis: the Comprehensive Assessment of At-Risk Mental States. 2005;39(11-12):964-971Pub Med Google Scholar Crossref Hodges A, Byrne M, Grant E, Johnstone E.

Neuroimaging predictors of transition to psychosis—a systematic review and meta-analysis. 2010;34(8):1207-1222Pub Med Google Scholar Crossref Fusar-Poli P, Perez J, Broome M, Borgwardt S, Placentino A, Caverzasi E, Cortesi M, Veggiotti P, Politi P, Barale F, Mc Guire P.

Neurofunctional correlates of vulnerability to psychosis: a systematic review and meta-analysis. 2007;31(4):465-484Pub Med Google Scholar Crossref Crossley NA, Mechelli A, Fusar-Poli P, Broome MR, Matthiasson P, Johns LC, Bramon E, Valmaggia L, Williams SC, Mc Guire PK.

Meta-analysis of Observational Studies in Epidemiology (MOOSE) group.

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