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Optimal performance is achieved with one set of gas sensors assigned to each animal chamber. Ebling Journal of Neuroendocrinology Volume 25, Issue 2, pages 180-189, February 2013 Intracerebroventricular Leptin Infusion Improves Glucose Homeostasis in Lean Type 2 Diabetic MKR Mice via Hepatic Vagal and Non-Vagal Mechanisms Xiaosong Li, Xhiping Wu, Raul Camacho, Gary J. doi:10.1371/0017058 A role for BDNF/Trk B signaling in behavioral and physiological consequences of social defeat stress M. In such case, data may be recorded at intervals as short as 10 seconds with all chambers operating in parallel. CLAMS-HC does not require any modification to your standard animal cage.

CLAMS-HC is designed to be affixed to any standard animal cage and provides an adaptable test environment with snap-in modules to support a broad array of physiological and behavioral monitoring capabilities.

CLAMS-HC provides an alternate housing solution that makes use of standard animal cages that support bedding and maintains the use of established standard animal cage cleaning protocols.

It is the measurement of mass, not volume, that allows Oxymax to be employed under various atmospheric conditions without the need to account for environmental pressure or temperature. Kozak and Muthu Periasamy The Journal of Biological Chemistry, March 30, 2015, doi: 10.1074/jbc.

The measurement of oxygen may be performed by these technologies supported by Oxymax: Paramagnetic O Sensor - [high speed] Provides full 0-100% range and high speed response Carbon Dioxide - is sensed by single beam non-dispersive IR (NDIR). 9 4216-4226 Activation of AMPKα2 in adipocytes is essential for nicotine-induced insulin resistance in vivo Yue Wu, Ping Song, Wencheng Zhang, Junhui Liu, Xiaoyan Dai, Zhaoyu Liu, Qiulun Lu, Changhan Ouyang, Zhonglin Xie, Zhengxing Zhao, Xiaozhen Zhuo, Benoit Viollet, Marc Foretz, Jiliang Wu, Zuyi Yuan & Ming-Hui Zou Nature Medicine (2015), doi:10.1038/nm.3826 Uncoupling Protein 1 and Sarcolipin Are Required to Maintain Optimal Thermogenesis and Loss of Both Systems Compromises Survival of Mice Under Cold Stress Leslie A. M115.637603 Coordination of the transcriptome and metabolome by the circadian clock Kristin L.

The method scores counts as ambulation when the animal traverses the cage, breaking a series of IR beams in sequence.

Repeated interruptions of the same IR beam do not incur ambulatory counts. All beam interruptions are scored as Total Activity. Subtraction of Ambulatory counts from the Total count provides counts associated with Stereotopy (grooming, scratching, etc.). Placement of IR photocells at a height above the animal detect rearing or jumping (Z-axis). Activity Scoring CLAMS-HC employs Columbus Instruments Opto-M4 or Opto-M5 Activity Monitor and patented (Pat: #4,337,726) process for the tabulation of activity counts associated with ambulation. Systems may be configured with single or multiple gas sensors. Nuotio-Antar, Naravat Poungvarin, Ming Li, Michael Schupp, Mahmoud Mohammad, Sarah Gerard, Fang Zou, Lawrence Chan Endocrinology, 3 August 2015 Lamp-2 deficiency prevents high-fat diet-induced obese diabetes via enhancing energy expenditure Mako Yasuda-Yamahara, Shinji Kume, Kosuke Yamahara, Jun Nakazawa, Masami Chin-Kanasaki, Hisazumi Araki, Shin-ichi Araki, Daisuke Koya, Masakzu Haneda, Satoshi Ugi, Hiroshi Maegawa, Takashi Uzu Biochemical and Biophysical Research Communications, 10 August 2015 Mice lacking prostaglandin E receptor subtype 4 manifest disrupted lipid metabolism attributable to impaired triglyceride clearance Yin Cai, Fan Ying, Erfei Song, Yu Wang, Aimin Xu, Paul M.

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